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Live Intranasal Influenza Vaccine Information Statement | CDC

Many countries recommend use of live attenuated influenza vaccines (LAIV) for children aged 2 years or older. The trivalent LAIV (LAIV-3) was licensed in the USA in 2003, and approved for use in the EU in 2011. The current quadrivalent formulation of LAIV (LAIV-4) obtained licensing during 2012-13, subsequently replacing LAIV-3.

Types of seasonal influenza vaccine - World Health Organization (WHO)

Our data provides evidence that the effect of LAIV on S pneumoniae density in children residing in an area of high pneumococcal carriage is modest and supports the wider rollout of LAIV in LMICs to help reduce the burden of influenza-related morbidity and mortality.

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